Name | Testosterone Enanthate |
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CAS NO | 315-37-7 |
EINECS | 206-253-5 |
Molecular Formula | C26H40O3 |
Molecular Weight | 401.6025 |
Other Name | (17beta)-3-oxoandrost-4-en-17-yl heptanoate testosterone enantate testosterone enthanoate 17-[(1-Oxoheptyl)oxy]androst-4-en-3-one; 17-Hydroxyandrost-4-en-3-one, 17-heptanoate; 3-Oxoandrost-4-en-17-yl heptanoate; 99% Testosterone Enanthate powder Factory hot selling Testosterone Enanthate cas315-37-7 CAS NO.315-37-7; 99% Testosterone Enanthate powder CAS NO.315-37-7; Andro L.A. 200;Androst-4-en-3-one, 17-[(1-oxoheptyl)oxy]-, (17beta)- |
Melting Point | 34-39℃ |
Boiling Point | 426.7°C at 760 mmHg |
Refractive Index | 1.56 |
Flash Point | 182.1°C |
Vapour Pressure | 4.54E-09mmHg at 25°C |
Safety Information | |
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Hazard Codes | T |
Risk Statements | 45-63 |
Safety Statements | 53-22-36/37/39-45 |
WGK Germany | 3 |
RTECS | XA3080000 |
HS Code | 2937290000 |
Testosterone enanthate Usage And Synthesis | |
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Indications and Usage | Testosterone enanthate is a type of androgen drug, and it is a synthetic compound of testosterone proprionate and testosterone enantate. Its effects are the same as those of testosterone acetate, which include promoting the development of male sex organs and secondary sex characteristics and resisting estrogen. It also has protein assimilating effects, which allow it to help muscle growth and weight gain. Testosterone enanthate can inhibit the pituitary gland and promote sex hormone secretion, thus decreasing the endogenous testosterone secreted by Leydig cells, which achieves the purpose of stopping spermatogenesis. Testosterone enanthate can be used as a long-term male birth control drug. It is clinically used to treat male hypogonadism and gonadal insufficiency, sex organ hypogenesis, infertility, eunuchism, and cryptorchidism. It can also be used to treat female dysfunctional uterine bleeding, menopausal syndrome, breast cancer and uterine cancer. It can also treat cirrhosis, aplastic anemia, osteoporosis and other consumptive diseases |
Drug Metabolism | After injection, it creates a blood concentration higher than the physiological level, and then blood concentration decreases rapidly |
Clinical Research | In a trial that injected monkeys with testosterone enanthate every week, the monkeys’ sperm cells began experiencing apoptosis in a week, with apoptosis rates peaking in the fifth week. A clinical trial with 308 participants also showed that testosterone enanthate’s birth-control effects are much more effective on Asian men than on Caucasian men, as over 95% of Asian men achieved azoospermia, while only 40-70% of Caucasian men did. A trial of over 100 volunteers showed that weekly muscle injections of 250mg led to most men developing azoospermia or severe ogliospermia in 10 weeks, and that sperm count could recover after ceasing injection for a certain period of time. If the injection intervals are extended to over 10-12 days, even increasing dosage will not have desired effects. Testosterone enanthate only needs to be injected once a week, which is an advantage over testosterone acetate. . |
Adverse reactions | Large dosages or extended use can cause water and sodium retention and edema. Young women may exhibit virilism, with characteristics including deepened voice, hair growth, acne, clitoral hypertrophy, etc. Not to be used by patients with prostatic cancer or pregnant patients. Should be used with caution by patients with prostate hypertrophy and liver and kidney dysfunction. When treating breast cancer, drug usage should be stopped immediately if hypercalcemia is detected |
Chemical Properties | White or yellowish-white, crystalline powder |
Originator | Delatestryl,Squibb,US,1954 |
Uses | Testosterone Enanthate is a derivative of testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells. |
Manufacturing Process | A mixture of testosterone, pyridine and oenanthic acid anhydride is heated for 1 1/2 hours to 125°C. The cooled reaction mixture is decomposed with water while stirring and cooling. After prolonged standing at a temperature below room temperature, the whole is extracted with ether and the ethereal solution is washed consecutively with dilute sulfuric acid, water, 5% sodium hydroxide solution, and again with water. The crude ester remaining on evaporation of the dried ether solution, after recrystallization from pentane, melts at 36° to 37.5°C. |
Therapeutic Function | Androgen |
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