| Name | Trenbolone acetate |
|---|---|
| Synonyms | Revalor-H Trenbolone acetate; Trenbolone Acetate 98%Min (Revalor-H); Trenbolone Acetate API; Trenbolone Acetate(Revalor-H); finaplix; ru1697; trienboloneacetate; revalor-h 17-BETA-(ACETYLOXY)ESTRA-4,9,11-TRIEN-3-ONE 17beta-hydroxyestra-4,9,11-trien-3-one 17-acetate 4,9,11-ESTRATRIEN-17-BETA-OL-3-ONE ACETATE revalor-h TRENBOLONE 17-ACETATE TRENBOLONE ACETATE 17-(acetyloxy)-(17-beta)-estra-11-trien-3-one 17-beta-acetoxy-delta-4,9,11-estratrien-3-one 17-beta-hydroxyestra-4,9,11-trien-3-oneacetate 9,11-trien-3-one,17-beta-hydroxy-estra-acetate finaplix ru1697 trienboloneacetate Trenbolone actetate TRENBOLONE ACETATE--DEA SCHEDULE*III ITE M Estra-4,9,11-trien-3-one, 17-(acetyloxy)-, (17.beta.)- trembolone acetate TRENBOLONE ACETATE/ENANTHATE 17β-Acetoxyestra-4,9,11-trien-3-one |
| CAS NO | 10161-34-9 |
| EINECS | 233-432-5 |
| Molecular Weight | 312.4 |
| Molecular Formula | C20H24O3 |
| Product Categories | Inhibitors; trenbolone series; Hormone Drugs; Finished Steroid and Hormone; Intermediates & Fine Chemicals; Pharmaceuticals; Steroids; Steroid and Hormone; Hormone |
| Mol File | 10161-34-9.mol |
| Trenbolone acetate Chemical Properties | |
|---|---|
| Melting point | 90-92°C |
| alpha | D20 +36.8° (c = 0.37 in methanol) |
| Boiling point | 392.32°C (rough estimate) |
| density | 1.1464 (rough estimate) |
| refractive index | 1.4618 (estimate) |
| storage temp. | 0-6°C |
| form | neat |
| EPA Substance Registry System | Trenbolone acetate (10161-34-9) |
| InChIKey | CMRJPMODSSEAPL-FYQPLNBISA-N |
| CAS DataBase Reference | 10161-34-9(CAS DataBase Reference) |
| Safety Information | |
|---|---|
| Hazard Codes | T |
| Risk Statements | 60 |
| Safety Statements | 22-36/37/39-45 |
| WGK Germany | 3 |
| RTECS | KG7753500 |
| HS Code | 2937290000 |
| Trenbolone acetate Usage And Synthesis | |
|---|---|
| Description | Trenbolone acetate (brand name: Revalor) is a 19-nortestosterone derivative and a synthetic, injected anabolic-androgenic steroid that is used in veterinary medicine. It is a highly efficient anabolic steroid that can greatly enhance the performance of athletes. Trenbolone acetate has several physiological effects. First, it can greatly promote insulin-like growth factor-1 (IGF-1). IGF-1 is a powerful and natural anabolic hormone that of great importance for muscle tissue development. Secondly, it can greatly increase the red blood cell count, further increasing blood oxygen and enhancing muscular endurance. Moreover, it can inhibit the glucocorticoid hormone, a hormone that destroy muscle tissue and promote fat. Finally, it can improve nutrient uptake and consumption efficiency. |
| Chemical Properties | Pale Yellow Solid |
| Originator | Parabolan,Negma,France,1980 |
| Uses | A steroid used to increase the muscle growth of livestock |
| Uses | anti-cataract agent |
| Manufacturing Process | Stage A: Preparation of 17β-Benzoyloxy-Estra-4,9,11-Trien-3-one - 0.400 g of 17β-benzoyloxy-4,5-seco-estra-9,11-diene-3,5-dione is dissolved in 4 cc of toluene under an inert atmosphere. The solution is cooled to 3°C, then 0.48 cc is added of the solution of sodium tert-amylate in anhydrous toluene, diluted by the addition of a further 4.8 cc of anhydrous toluene. This reaction mixture is kept between 0°C and +5°C for six hours, with agitation and under an inert atmosphere, then 5 cc of a 0.2 N solution of acetic acid in toluene are added. The mixture is extracted with toluene, and the extracts are washed with water and evaporated to dryness. The residue is taken up in ethyl acetate, and then the solution is evaporated to dryness in vacuo, yielding a resin which is dissolved in methylene chloride, and the solution passed through a column of 40 g of magnesium silicate. Elution is carried out first with methylene chloride, then with methylene chloride containing 0.5% of acetone, and 0.361 g is thus recovered of a crude product, which is dissolved in 1.5 cc of isopropyl ether; then hot methanol is added and the mixture left at 0°C for one night. 0.324 g of the desired 17β-benzoyloxy-estra-4,9,11-trien-3-one are thus finally obtained, being a yield of 85%, melting point is 154°C. Stage B: Preparation of 17β-Hydroxy-Estra-4,9,11-Trien-3-one - 3 g of 17β- benzoyloxy-estra-4,9,11-trien-3-one, obtained as described in Stage A are dissolved in 15 cc of methanol. 0.03 g of hydroquinone is added, and the mixture is taken to reflux while bubbling in nitrogen. Then 1.2 cc of 11% methanolic caustic potash is added and reflux is maintained for three hours, after which the reaction product is acidified with 0.36 cc of acetic acid. The methyl benzoate thus formed is eliminated by steam distillation, and 2.140 g of crude product are obtained, which are dissolved in 20 cc of methylene chloride. This solution is passed through 10 parts of magnesium silicate, elution being performed with 250 cc of methylene chloride containing 5% of acetone. After evaporation of the solvent 2.050 g of product is recovered, which is recrystallized from isopropyl ether. In this way 1.930 g of the desired 17β-hydroxy-estra-4,9,11-trien-3-one is obtained being a yield of 89%, melting point is 186°C. It is converted to the acetate by acetic anhydride. |
| Brand name | Trenbolone is INN and BAN. |
| Therapeutic Function | Anabolic steroid |
| References | https://en.wikipedia.org/wiki/Trenbolone_acetate Henricks, D. M., et al. "Serum concentrations of trenbolone-17 beta and estradiol-17 beta and performance of heifers treated with trenbolone acetate, melengestrol acetate, or estradiol-17 beta." Journal of Animal Science 75.10(1997):2627-33. https://www.steroid.com/trenbolone-acetate.php |
| Trenbolone acetate Preparation Products And Raw materials | |
|---|---|
| Raw materials |
Methanol-->Acetic acid-->Sodium tert-pentoxide-->ETHYLENEDIAMINE TETRAKIS(PROPOXYLATE-BLOCK-ETHOXYLATE) TETROL-->Acetic anhydride
|
| Package method |
|---|
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