Name | Epiandrosterone |
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Synonyms | 3BETA-HYDROXY-5ALPHA-ANDROSTAN-17-ONE 3BETA-HYDROXYETIOALLOCHOLAN-17-ONE 3-HYDROXY-10,13-DIMETHYLHEXADECAHYDROCYCLOPENTA[A]PHENANTHREN-17-ONE (3S,5S,8R,9S,10S,13S,14S)-3-HYDROXY-10,13-DIMETHYL-HEXADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-17-ONE 5A-ANDROSTAN-3B-OL-17-ONE 5ALPHA-ANDROSTAN-3BETA-OL-17-ONE EPIANDROSTERONE EPLANDROSTERONE ISOANDROSTERONE TRANS-ANDROSTERONE (3S,5S,8R,10S,13S)-3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-one 3beta-Androsterone 3-Epiandrosterone 3-Hydroxyandrostan-17-one 5alpha-Androstan-17-one, 3beta-hydroxy- 5-Epiandrosterone-17-one Androstan-17-one, 3-hydroxy-, (3beta,5alpha)- Androsterone, (3beta)- Androsterone, epi- Androsterone, trans- |
CAS NO | 481-29-8 |
EINECS(EC#) | 207-563-3 |
MDL Number | MFCD00064134 |
Molecular Weight | 290.44 |
Molecular Formula | C19H30O2 |
Epiandrosterone Chemical Properties | |
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Melting point | 172-174 °C |
alpha | 91 º (c=1, CH3OH) |
density | 1.0320 (rough estimate) |
Boiling point | 372.52°C (rough estimate) |
storage temp | Refrigerator |
CAS DataBase Reference | 481-29-8(CAS DataBase Reference) |
refractive index | 1.4709 (estimate) |
pka | 15.14±0.60(Predicted) |
Water Solubility | practically insoluble |
InChIKey | QGXBDMJGAMFCBF-LUJOEAJASA-N |
Merck | 3609 |
BRN | 1884007 |
NIST Chemistry Reference | 3Beta-hydroxy-5alpha-androstan-17-one(481-29-8) |
Safety Information | |
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Safety Statements | 22-24/25 |
WGK Germany | 2 |
HS Code | 29144000 |
F | 21 |
Epiandrosterone Usage And Synthesis | |
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Chemical Properties | white to off-white crystalline powder |
Uses | A steroid hormone that is present in normal human urine as a minor constituent, it is a less active 3β-isomer of the androgen Androsterone (A635535). Controlled Substance |
Uses | Anabolic steroid |
Definition | ChEBI: A 3beta-hydroxy steroid that is (5alpha)-androstane substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. |
Purification Methods | Purify epi-androsterone via the acetate, hydrolyse this and recrystallise it from CHCl3/hexane or aqueous EtOH. The acetate [1239-31-2] is purified by chromatography and when crystallised from pet ether has m 103-104o, []D +68.5o (c 1, CHCl3). The oxime has m 194-196o (from MeOH), []D +17.5o (c 6.2, CHCl3). The racemic ketone is sublimed at 130o/high vacuum and after two crystallisations from methylcyclohexane it gives prisms with m 161-162o (which changed crystal form at 140-145o). [Ruzicka & Wettstein Helv Chim Acta 18 1264 1935, Johnson et al. J Am Chem Soc 75 2275 1953, 78 6331 1956, Cordwell et al. J Chem. Soc 361 1953, Beilstein 8 IV 462.] |
Epiandrosterone Preparation Products And Raw materials | |
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Raw materials | Epiandrosterone acetate-->5-ALPHA-ANDROSTANE |
Preparation Products | 17-Methyltestosterone-->Androst-3-ol-17-one 3-p-toluenesulfonate |
Package method |
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